Introducing the Most Comprehensive Analysis of Ketamine’s Effectiveness on the Web

Most people considering ketamine therapy are flying blind.

You’ll see headlines that say it’s a miracle, and studies that say it’s a dud. Clinics quote stats you can’t trace, while TikTok shows you trip videos that tell you nothing. And if you’re depressed, you don’t have time for hype or confusion.

That’s what drove me to create this report.

I wanted to answer the most important questions for someone like me—someone trying to survive long enough to get better:
How many people actually respond to ketamine? How many go into remission? And how fast?

Let’s break that down.

A response means your symptoms drop by at least 50%. Remission means you feel normal again—like the depression has lifted entirely.

Those are the numbers that matter. Not the vibes. Not the Instagram testimonials. The numbers.

Why I Only Used Systematic Reviews and Meta-Analyses

If you look at individual studies on ketamine, you’ll get whiplash.

One says IV ketamine works in 2 days. Another says it’s no better than a placebo. A third says oral ketamine is garbage—right next to one that says it saved someone’s life.

So how do you know what’s real?

You go up a level.

Systematic reviews take dozens of studies and analyze them together.
Meta-analyses crunch the numbers across all those studies to give you an average effect.

That’s how the medical community gets its answers. That’s how new standards of care are born. And that’s the level I used.

This report doesn’t cherry-pick. It synthesizes the best available evidence from the last five years—25+ reviews in all.

Why It’s Credible

This isn’t just a blog post. It’s not something I tossed on Medium and called a study.

Four of the most respected open science platforms accepted it as a scientific report:

• Zenodo, built by CERN—yes, the same CERN that created the World Wide Web—hosts peer-reviewed research from around the globe.

• SSRN, used by top academic institutions and clinicians to share working papers before formal journal publication.

• Figshare, a repository used by researchers at universities and hospitals to archive preprints and datasets.

• OSF (Open Science Framework), a platform trusted by scientists for transparent, reproducible research.

None of these are pay-to-play. You can’t just upload and hit publish. They review what’s submitted. And they accepted this report because it does what it says it does:
Compiles the best science on ketamine therapy’s effectiveness into one clear, unbiased summary.

If you’re trying to decide whether ketamine therapy is worth it, this report won’t give you marketing copy. It’ll give you clarity.

You can read it below—no email, no download, no pitch. Just the facts.